| Item Type | Name |
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Concept
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Cell Adhesion
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Concept
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Focal Adhesions
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Concept
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Cell Adhesion Molecules
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Concept
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Platelet Endothelial Cell Adhesion Molecule-1
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Concept
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Focal Adhesion Protein-Tyrosine Kinases
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Concept
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Focal Adhesion Kinase 1
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Concept
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Substrate Specificity
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Concept
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Crk-Associated Substrate Protein
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Concept
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Focal Adhesion Kinase 2
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Academic Article
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p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl.
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Academic Article
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Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL.
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Academic Article
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p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene.
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Academic Article
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BCR/ABL induces multiple abnormalities of cytoskeletal function.
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Academic Article
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The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells.
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Academic Article
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Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells.
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Academic Article
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Role of focal adhesion proteins in signal transduction and oncogenesis.
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Academic Article
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The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase.
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Academic Article
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The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin.
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Academic Article
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Expression of the focal adhesion protein paxillin in lung cancer and its relation to cell motility.
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Academic Article
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Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with beta 1 integrin- and phosphatidylinositol 3-kinase-dependent PKC alpha activation.
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Academic Article
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The noncatalytic domain of protein-tyrosine phosphatase-PEST targets paxillin for dephosphorylation in vivo.
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Academic Article
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A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion.
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Academic Article
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A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration.
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Academic Article
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Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells.
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Academic Article
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Role of the cytoskeletal protein paxillin in oncogenesis.
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Academic Article
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Cell motility, adhesion, homing, and migration assays in the studies of tyrosine kinases.
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Academic Article
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c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions.
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Academic Article
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Fibronectin enhances viability and alters cytoskeletal functions (with effects on the phosphatidylinositol 3-kinase pathway) in small cell lung cancer.
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Academic Article
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2-methoxyestradiol alters cell motility, migration, and adhesion.
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Academic Article
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Integrin-dependent protein tyrosine phosphorylation is a key regulatory event in collagen-IV-mediated adhesion and proliferation of human lung tumor cell line, Calu-1.
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Academic Article
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Lymphatic vessel density is not associated with lymph node metastasis in non-small cell lung carcinoma.
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Academic Article
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EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation.
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Academic Article
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Fyn: a novel molecular target in cancer.
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Academic Article
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c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.
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Academic Article
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FYN is overexpressed in human prostate cancer.
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Academic Article
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Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.
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Academic Article
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Involvement of the adapter protein CRKL in integrin-mediated adhesion.
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Academic Article
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Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity.
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Academic Article
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Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL.
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Academic Article
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Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: relevance to lung cancer.
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Academic Article
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c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury.
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Academic Article
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Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
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Academic Article
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FAK and paxillin, two potential targets in pancreatic cancer.
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Academic Article
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Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma.
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Academic Article
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Prolonged Pharmacokinetic Interaction Between Capecitabine and a CYP2C9 Substrate, Celecoxib.
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Academic Article
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Effects of selected deubiquitinating enzyme inhibitors on the proliferation and motility of lung cancer and mesothelioma cell lines.
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Grant
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Role of Paxillin in Lung Cancer
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